目录号 | R19001M3F2 |
克隆号 | 3F2 |
抗体类型 | Rabbit IgG |
实验应用 | ELISA , FC |
推荐稀释比例 | 10ug/mL |
种属反应性 | Human CD54 |
免疫原 | CD54 ECD protein |
存储缓冲液 | ≤ -20 °C |
CD54 (Cluster of Differentiation 54) is also known as ICAM-1 (Intercellular Adhesion Molecule 1). It is a cell surface glycoprotein which is typically expressed on endothelialcells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is the receptor of rhinovirus for entry into respiratory epithelium. ICAM-1 can be induced by interleukin-1 (IL-1) and tumornecrosis factor (TNF) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrateinto tissues.
ITA :Immuno Turbidimetric assay
WB: Western Blot
IF: immunofluorescence
IP: Immuno precipitation
ELISA: Enzyme-linked Immunosorbent assay
IHC: Immunohistochemistry
FC: flow cytometry
No biohazard
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