目录号 | R16016M116 |
克隆号 | MM116 |
抗体类型 | Mouse IgG |
实验应用 | IHC |
推荐稀释比例 | 1:100-1:400 |
种属反应性 | Human p16 |
免疫原 | Full length recombinant human p16 protein |
存储缓冲液 | Tris Buffer,pH7.3-7.7,with1%BSA and 0.09%Sodium Azide |
The p16 (p16INK4A) protein is a cyclindependent kinase (CDK) inhibitor that plays an important regulatory role in the cell cycle. By controlling the transition between the G1 and S phases through regulation of retinoblastoma protein, p16decelerates cellular differentiation and therefore acts as a tumor suppressor, making it the key marker in several human cancers including head and neck cancer, perianal lesions, melanomas, gliomas, lymphomas, and some types ofleukemia. p16 is also clinically indicated in carcinomas of the esophagus, pancreas, lung, biliary tract, liver, colon, and urinary bladder.
Shipped at 4°C. Store at +4°C short term (2-4 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
WB: Western Blot
IF: immunofluorescence
IP: Immuno precipitation
ELISA: Enzyme-linked Immunosorbent assay
IHC: Immunohistochemistry
FC: flow cytometry
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