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单克隆抗体

p16(MM116)鼠单克隆抗体

一般信息 / General Information

目录号 R16016M116
克隆号 MM116
抗体类型 Mouse IgG
实验应用 IHC
推荐稀释比例 1:100-1:400
种属反应性 Human p16
免疫原 Full length recombinant human p16 protein
存储缓冲液 Tris Buffer,pH7.3-7.7,with1%BSA and 0.09%Sodium Azide

背景 / Background

The p16 (p16INK4A) protein is a cyclindependent  kinase  (CDK)  inhibitor that plays  an important  regulatory  role in the cell  cycle. By controlling  the  transition between the G1  and S phases through regulation of retinoblastoma protein, p16decelerates  cellular  differentiation and therefore acts  as a tumor suppressor, making it the  key  marker  in  several   human cancers including head and neck cancer,  perianal  lesions,  melanomas, gliomas, lymphomas, and some types ofleukemia. p16 is also clinically indicated in carcinomas of the esophagus, pancreas, lung, biliary tract, liver, colon, and urinary bladder.

图片 / Picture

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存储条件 / Storage

Shipped at 4°C. Store at +4°C short term (2-4 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.


缩略语 / Abbreviations

ITA :Immuno Turbidimetric assay
WB: Western Blot
IF: immunofluorescence
IP: Immuno precipitation
ELISA: Enzyme-linked Immunosorbent assay
IHC: Immunohistochemistry
FC: flow cytometry
 

生物危害 / Hazard/Biohazard

This antibody contains 0.09% sodium azide as preservative.Please handle and dispose the product properly. No known biohazard is associated with this product.
 

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